• Patients randomised:
  • 1600
  • Sites active:
  • 42

Brief Summary

A multi-centre, randomised controlled trial of early goal-directed therapy in patients presenting to the Emergency Department with severe sepsis in Australasia

The trial commenced enrolment in October 2008.

Chief Investigator

Professor Rinaldo Bellomo
Staff Specialist, Intensive Care Unit
Austin and Repatriation Medical Centre
Austin Campus, Heidelberg
Victoria 3084, Australia
Ph: +61 3 9496 5992
Fax: +61 3 9496 3932
Email: Rinaldo.BELLOMO@austin.org.au

Coordinating Centre

The Australian & New Zealand Intensive Care Research Centre
Department of Epidemiology and Preventive Medicine
School of Public Health and Preventive Medicine
Monash University
The Alfred, Commercial Road, Melbourne
Victoria 3004, Australia
Phone: +61 3 9903 0340
Fax: +61 3 9903 0071

This study is endorsed by the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Australasian College for Emergency Medicine Clinical Trials Group


The ARISE study is funded by a project grant from the National Health and Medical Research Council (NHMRC) (Project grant no. 491075). The ANZIC-RC will supply infrastructure and administrative support.

For further information

Contact Belinda Howe